The Group for Integrity of Materials and Structures is divided into four teams. It is the objective to improve the limit state analysis of mechanically stressed components. The emphasis is on the descriptions of strain hardening and failure mechanisms on different length scales. The first team, Structural Integrity, is primarily concerned with the development of concepts to fully exploit mechanical property profiles of structural materials in the framework of structural integrity assessments. In the second group, Lifetime Assessment, new concepts to numerically assess the component´s lifetime are developed and experimentally validated. The Damage Tolerance group deals with the microstructure based characterization of damage evolutions and damage tolerances of modern material concepts. Together the three groups form a complementary pattern and offer innovation potential for infrastructure and energy conversion equipment. As a cross-sectoral topic, the multi-axial component testing serves to validate the newly-developed concepts.